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doi: 10.1038/ejcn.2014.237 35 Cigarran GuldrisS.Gonzlez ParraE.Cases AmensA

Targeting host defense system and rescuing compromised mitochondria to increase tolerance against pathogens by melatonin may impact outcome of deadly virus infection pertinent to COVID-19

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Since our data suggest that the urea cycle in AKI is already overloaded, it is uncertain what levels of protein intake are necessary to meet metabolic needs and at what point a high protein intake will overwhelm the urea cycle and ammoniagenesis